Randy Sandke (born 1949 in Chicago) is a jazz trumpeter and guitarist.

In an interview with Larry Kart he said: "I got into jazz kind of chronologically, beginning with Bix and Louis, then Dizzy, Clifford Brown, Miles, and Freddie Hubbard. I also studied at Roosevelt University with Renold Schilke, a legendary teacher and maker of trumpets who was with the Chicago Symphony for years". His high-school band included future luminaries Ray Anderson and George Lewis; when he went to Indiana University, he met Michael Brecker and formed a jazz-rock band. He was offered a job with Janis Joplin, but a hernia of the throat had by then made it impossible for him to play.