Margaret Singana (Margaret Mcingana, 1938 in Queenstown, Eastern Cape – 2000) was a South African musician. In the 1950s, she moved from Queenstown, Cape Province to Johannesburg in the then Transvaal, where she found work as a domestic servant.

It was while cleaning other people's houses that Margaret Singana was 'discovered'. She used to sing while cleaning. Her employers were so impressed that they recorded her singing and sent the tape to a record company. The producers of the musical Sponono, written by Alan Paton, gave her a part as a chorus singer in 1964.