Port O'Brien was an American musical group combining elements of acoustic, folk and indie rock.

They were named after a bay in Alaska featuring a now-abandoned cannery on Kodiak Island where founder member Van Pierszalowski's parents met. They started out as a folk music duo of Cambria Goodwin and Van Pierszalowski while Cambria was living in Cambria, California and Van was living in Oakland. After Cambria moved closer to Oakland they added a rhythm section composed of Caleb Nichols and Joshua Barnhart.