For the radio personality, see Little Walter DeVenne.

Little Walter, born Marion Walter Jacobs (May 1, 1930 – February 15, 1968), was an American blues musician and singer, whose revolutionary approach to the harmonica earned him comparisons to Charlie Parker and Jimi Hendrix, for innovation and impact on succeeding generations. His virtuosity and musical innovations fundamentally altered many listeners' expectations of what was possible on blues harmonica. Little Walter was inducted to the The Rock and Roll Hall of Fame in 2008 in the "sideman" category making him the first and only artist ever inducted specifically as a harmonica player.