Loose Fur is an American rock band comprising Wilco members Jeff Tweedy and Glenn Kotche, and Wilco collaborator Jim O'Rourke. The trio first convened in May 2000 in preparation for a Tweedy performance at a festival in Chicago. Tweedy was offered the opportunity to collaborate with an artist of his choosing, and he decided to work with O'Rourke. O'Rourke brought Kotche to a rehearsal session, and the trio recorded an album's worth of songs. The trio have since released two albums, 2003's Loose Fur and 2006's Born Again in the USA, for Drag City. The band has only toured once.

The band is noted for its influence on Wilco's fourth album, Yankee Hotel Foxtrot. Tweedy was unhappy with how music from the initial recording sessions for the album was sounding, resulting in a lineup change for the band. Both O'Rourke and Kotche replaced members of Wilco during the recording sessions for the album, and both contributed to the band's recordings through 2007's Sky Blue Sky. Kotche remains a member of Wilco as of 2014.