Una Mae Carlisle (December 26, 1915 – November 7, 1956) was an American jazz singer, pianist, and songwriter.

She was born in Xenia, Ohio. Fats Waller discovered Carlisle when she was still in her teens, while she worked as a local Cincinnati performer live and on radio. Carlisle's piano style was much influenced by Waller's; she played in a boogie-woogie/stride style and incorporated humor into her sets. She played solo from 1937, touring Europe repeatedly and recording with Waller late in the 1930s.