The Five Keys is an American rhythm and blues vocal group that was instrumental in shaping this genre in the 1950s.

It was formed with the original name of Sentimental Four in Newport News, Virginia, U.S., in the late 1940s, and initially consisted of two sets of brothers - Rudy West (born 25 July 1932, Newport News, Virginia) and Bernie West (born 4 February 1930, Newport News), and Ripley Ingram (born 1930 - died 23 March 1995, Newport News) and Thomas Threat. Ingram left in 1949 and Maryland Pierce (born 1933) and Dickie Smith became members in his place. At this juncture the name of the group was changed to The Five Keys.