David Rose may refer to:
- David Rose (animator) (1910–2006), animator
- Dave Rose (basketball) (born 1957), head basketball coach at Brigham Young University
- David Rose (Guyanese politician) (1923–1969), Governor Central of Guayam
- David Rose (journalist) British writer and journalist
- David Rose (producer) (born 1924), BBC Television drama producer; Commissioning editor for Fiction at Channel 4
- David Rose (real estate developer) (1892-1986), American real estate developer and philanthropist
- David Rose (rugby) (born 1931), Scottish rugby union and Great Britain rugby league footballer
- David Rose (songwriter) (1910–1990), an American songwriter, composer, arranger and orchestra leader. Judy Garland's first husband.
- David Rose (UK politician), Northern Irish unionist politician
- David L. Rose (born 1967), U.S. business executive and scientist at the MIT Media Lab
- David S. Rose (born 1957), technology entrepreneur and angel investor
- David Stuart Rose (1856–1932), mayor of Milwaukee, Wisconsin, USA
