Philly's Most Wanted was an American hip hop duo composed of Al "Boo-Bonic" Holly and Joel "Mr. Man" Witherspoon and DJJay Faire. The duo broke into the music business as affiliates of production duo, The Neptunes.

The duo signed with Atlantic Records in 2000 and issued their first two singles, "Y'all Can't Never Hurt Us" and "Cross the Border" soon after. The latter song peaked at #98 on the Billboard Hot 100 and 3 on the Billboard Hot Rap Singles. Their debut album, Get Down or Lay Down, however, was delayed for over a year, finally being released on August 7, 2001. Despite production from The Neptunes, the album failed commercially, only reaching No. 69 on the Billboard 200.