Billy Butterfield (January 14, 1917 in Middleton, Ohio – March 18, 1988) was a band leader, jazz trumpeter, flugelhornist and cornetist.

He studied cornet with Frank Simons, but later switched to studying medicine. He did not give up on music and quit medicine after finding success as a trumpeter. Early in his career he played in the band of Austin Wylie. He gained attention working with Bob Crosby (1937–1940), and later worked with Artie Shaw, Les Brown, and Benny Goodman.