Os Mutantes ("The Mutants"), (Portuguese pronunciation: [uz muˈtɐ̃tʃis]) are an influential Brazilian psychedelic rock band that were linked with the Tropicália movement of the late 1960s.

Although the original line-up (Rita Lee, Arnaldo Baptista and Sérgio Dias; and later with Liminha and Dinho Leme) made the most notorious breakthrough for the group, it has gone through numerous personnel changes throughout its existence. After a hiatus from the late 1970s to the early 2000s, the band reunited in 2006, touring and recording new material.

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