Q Lazzarus (born 1965) is an American singer, best known as a one-hit wonder for the 1988 song "Goodbye Horses", which was featured in Married to the Mob, The Silence of the Lambs (the Buffalo Bill song), Clerks II (imitating Silence of the Lambs), Lakai Footwear's Fully Flared, Unhinged: The Jesse Hicks Story (also imitating Silence of the Lambs), Maniac (2012 film), Rockstar's video game Grand Theft Auto IV, EA's video game Skate 3, and TV shows Family Guy (also imitating Silence of the Lambs) and Nip Tuck. The music and lyrics of the song were written by William Garvey. It was originally recorded by Q Lazzarus in 1988, but later re-released as a single in 1991, with a greater duration, as a result of its appearance in Silence of the Lambs. The infamous scene in which the track plays has garnered it the popular nickname "The Buffalo Bill Song".

Q Lazzarus appeared in the 1986 film Something Wild performing "The Candle Goes Away" and in the 1993 film Philadelphia performing "Heaven" from the Talking Heads album Fear of Music. She also contributed music to the 1996 underground film Twisted.