Negative FX was a hardcore band from Boston, formed in 1981. Though the band lasted only a short time, playing a total of five shows (six flyers exist), the band was well known for their involvement in the local straight edge scene of the early 1980s. Along with members of the bands DYS and SS Decontrol (SSD), Negative FX was part of the "Boston Crew", a group of social friends who traveled around the country with SSD and other Boston hardcore bands.

Negative FX played fast and unmelodic hardcore punk that often featured shouted gang vocals on the songs' choruses. The band members consisted of Patrick Raftery on guitar, Rich Collins on bass, Dave (Bass) Brown on drums, and high-profile vocalist Jack Kelly, who frequently went by the name of "Choke". Kelly went on to form the bands Last Rights and Slapshot.