Daniele Sepe (born April 17, 1960 in Naples) is an Italian musician, known internationally for interpreting protest songs from around the world.

His first instrument was the flute, which he played at the San Pietro a Majella conservatoire. After graduating, he began performing with the Gruppo operaio 'E Zezi di Pomigliano d'Arco, playing at numerous festivals and recording a few albums.