Thalia Zedek (born 1961) is an American singer and guitarist. Active since the early 1980s, she has been a member of several notable alternative rock groups, including Live Skull and Come. Critic Heather Phares writes that Zedek's music can be defined by "the permanent, aching rasp in her voice, her guitar's bluesy bite, the startlingly clear-eyed lyrics about life and loss."